They both chew up tons of stamina and makeit diificult at early levels, but there are ways to make any build feasible in Skyrim.
This ^
You won't get any race related bonuses.
Argonians are better suited to a light armored ninja assassin type build.
I can't remember their racial credited skills but i thinks its something like sword / dagger, illusion, sneak, archery, alchemy etc
But like said. This is just the starting off and early levels. All TES games make it so you can be anything you want with any race.