Apologies if this one has already been answered, but I've searched the forums and have drawn blanks thus far...

I have the Coral Claw (purchased rather than found), but it will not unlock the door. I have re-loaded and re-visited, I have even attempted using every other combination on the off-chance that the inscription on the claw is wrong, I have dropped, stored and re-acquired the claw (as suggested elsewhere online), but I still cannot gain access to the locked door.

Very frustrated.

Can anybody help please?

Are you using a console version or computer version?

Exit the dungeon and re-enter, also try re-loading a previous save (before entering) this is a known bug, where the puzzles some times don't work.

360 version.

To be fair, I have played for many, many hours and this is the first real glitch I have come across.

Best go by DPPredator's suggestions then. I don't have any experience with the console versions.