All i know is that about 40hrs after being in Vault 11 and upon first entering the strip, Victor the cowboy robot greets me and tells me to head to the Lucky 38 as soon as possible. I follow him there and his face turns from cowboy to cop and his corpse is lying on the stairs of the Lucky 38. When we zone in he and two other robots attack us and the whole casino is agro. Apparently killing the Vault 11 robots gets an unknown robot bad faction. I am not sure what quests involve Vault 11, but don't go there unless you absolutely have to and only after you have your suite in the Lucky 38. Hopefully this is a major bug that will be fixed with the upcoming patch since it would be ludicrous to allow players to explore areas that would ruin the main quest line by simply fighting robots that attack you. Either lock Vault 11 until you get whatever quest or have the robots respawn if they are needed for a specific quest.
This has not been confirmed by the devs as being the incident that bugged the Lucky 38, but I did get a failed quest message after killing the robots and others have posted this is the issue. I am not re-doing over 40hrs of the game so I guess if they don't fix it I will have to side with Mr. Yes Man to finish the game and will never be able to get my suite. I reloaded a saved game prior to entering the strip and have been exploring everywhere else I can prior to going back to the strip in hopes the patch will fix this issue before going back to the strip for the first time on this saved game.