If you're having problems loading saved games since Title Update #4, since Bethesda won't help you, this is a quick fix. This worked for me. It may not be a permanent solution.

1. Start a new game
2. Play till you reach the outside of Doc Mitchell's house.
3. Save your game.
4. Attempt to load a previous character save.

Save should load with no problem. I'm very disappointed in the lack of interest of Bethesda in reassuring fans that this problem will be fixed immediately. Hopefully this will help people that are in the dark. :violin: