So i open up my Pipboy after i had just leveled up my guns to 60 and look at it and it says - 59 (-)... where did the negative come from and why did it take away a point? this happened for a bunch of them. two of the ones had +'s after them. also on the S.P.E.C.I.A.L my endurance was at 5 and i looked at it and said 4(-)
As Nessh said. It could be from any number of various effects; suffering from drug withdrawals, a crippled limb, negative effects from certain consumables, radiation, etc.