So far (I'm currently level 7 on the default difficulty) and I had to run away on several occasions.
There are some... things... in the wilderness, that are really scary.
Seems like they put in some monsters by hand (not spawning randomly), that will obviously kick you around at low level but even some of the random encounters can be quite devious.
The combat is also lot rougher in Skyrim compared to Oblivion.
An average enemy can kill you in 2 - 5 strikes, so fighting multiple enemies is always dangerous.
You have to make use of your surroundings and think (some enemies are weak to fire etc...), rather than spamming the same attack/heal pattern over and over again until everything stops moving. So far it seems they really nailed it this time.