Can somebody give me a step by step on how to set spells to my hotkeys.I got 2 weapons set last night but I can't get the spells.I'm following the manual instructions but I must be doing something wrong.My brain is still in New Vegas and I'm having a hard time getting used to the controls.Thanks.

Same way weapons are done. I add them to favourites, hover over them in the list then push the key I want to use.

Is that what you're doing?

I'm struggling a bit too, and it doesn't help that if you change the keymapping, you can no longer hotkey or favorite anything. I really hope that gets fixed.

But shouldn't spells work the same way as weapon?

Inventory > Favorite > Exit, Open Favorites > Hit Number Key for hotkeying.

Yes.I did the weapons last night so I don't remember exactly what I did.

For me, this worked:

1) Go to either weapons or magic.
2) Cursor to desired weapon/spell and press 'F'. You might have to use the WASD keys to highlight the correct item if your mouse doesn't work right (a bug some people are having).
3) Once the item is 'favorite-ed', exit from the inventory.
4) When you're completely out of the inventory screen, press 'Q'. This brings up Favorites.
5) Highlight whichever item in your favorite list that you want to hotkey and press a number key (1-8). Now that item will be bound to your number key of choice.

Hope this helps!

That's the problem I'm having.It say's favorite but when I go to my favorites list it's not there to key.

Oh! Wow, that's strange. Errr.... I have no idea what to say. If it's a bug, which it sounds like it is, then hopefully they'll patch it soon. I hope I don't experience that bug!