I've been playing for around 25 hours now, I'm level 27 and about 1/3 through the main quest. I just finished killing a dragon in Riverwood and fast travelled to my Breezehome, and now I can't interact with things properly.

I can talk to NPCs, use the storage in my home and use doors, but pressing X on Alchemy tables, enchantment tables, any type of smithing/crafting table doesn't work. I spend most of my time doing those sort of activities, so having them not work is kinda killing the game for me. I've not heard much about this bug from other people, but I do know I'm not the only one it has happened too.

Before this I've had no problems at all with lag or any other bugs. Does anyone know a workaround?

Welcome to Skyrim, on the PS3, Home to the worlds worst Gaming Port.

What is the size of your latest saved data file?

Just checked, 5401KB at 29 Hours and 40 mins play time.

Wow, mine exceeded 7000 at level 14 with just under 20 hours of play.