A few minutes ago, I decided to boot up Skyrim again, and decided that I'll try to mitigate the lag with shorter gameplay sessions and when it becomes unbearable to reboot and restart from a manual save point. At present, I'm running Skyrim on a PS3 slim (with a 500gb hd), and autosave turned off. I also rebuilt the database a few days ago. It started off ok, but as of a few minutes ago, audio was completely out of sync, and the lag returned after probably 15 minutes of playing. Has anyone else experienced something similar?