Do skills like Alchemy and Smithing still screw up the leveling curve the way they did in Morrowind and Oblivion? IE, if you stop and make yourself a bunch of potions at low level, will you end up jumping five levels and getting your rear handed to you because you still have low level fighting skills? Is it enough of an issue that it is necessary to actively avoid using Alchemy like in vanilla Oblivion?
