I don't get it I was just playing DA Origins at 3AM Monday Morning and it worked just fine, I tried to play today and it says that.dll is missing, is there a place to install the .dll? I have it on steam and am using an ATI Video Card.

Try reinstalling PhysX.

Navigate to the install disc of DAO then go to the \software folder and run the program PhysX_9.09.0408_SystemSoftware. That will install PhysX onto your computer. Or you could download the latest version from Nvidia's site.

It is already installed, when I try it says "the current installed version of PhysX is better than the version you are trying to install" So I guess it thinks that PhysXLoader.dll is not on my computer for some reason. I can navigate to C:\Program Files (x86)\NVIDIA Corporation\PhysX\Common and see it in the fodler.