Basically, enchanting or alchemy? obviously.

A strong potion can exceed the most powerful of enchantments, giving you a great boost, albeit for a limited amount of time. For 60 seconds, in rare times 300, you are as strong as they come, felling usually insurmountable foes and taking blows that would kill a man of lesser stature.

An enchantment, once applied to a piece of your apparel, is a constant boost, always there. Giving you the comfort of not having to worry about running out. Always-on no need to re-apply. Through multiple enchantments you can boost your skills to unparalleled levels, becoming nigh-invincible if you so wish.

So which do you prefer?

Isn't this already in the Series Discussion?
Anywho, for me it's enchantments. I prefer the constant effect as opposed to the timed one, and the ability to have to enchantments on one item - via the perk - is extremely useful.

Meh I have to say I prefer enchantments because I can put soul trap on weapons potions can't do that

What's with those poison potions everywhere anyways?

Enchantments for boosts, potions for restoration.