At first the Giants should be hostile, and the way it is in the game where they only bother you if you bother them is fine.
However, it might be nice to be able to befriend them, or maybe a camp. Perhaps a quest where the choice to help them or not lies with you. While they would not become friends to talk to and the like, it would be like that one Foresworn place that is peaceful to you or hostile depending on how you do one of the quests in the game. However, other than the curiosity of being surrounded by Foresworn that don't want to skin you alive there is no reason to go to this camp.
I do have to say it is fun to go on a Cheese raid and avoid their blows as I sprint through the camps.
While I agree that it's not really necessary, I think it'd be interesting if you could find a book that allowed you to get a very basic level of understanding of their language, which would open the door for a questline that allows you to learn more of their language and befriend them more. While I don't think they'd have any use for money, it'd be cool to see a different barter system of skulls, pelts, and other items, used for you to be able to trade with them.