that would set me back to level 1
From here on out you should probably start using around 5 or so saves and save on the oldest one first. When you have a save from a couple hours ago it's better to just redo what you did in that time than be completely out of luck.
I use 5 saves and had to go back and redo about an hour and a half of stuff once, but at least I didn't have a glitched game. It's a good idea to have many saves on pretty much every game Bethesda makes.