I posted this already in the cheats hints and spoiler section, though, literally no one is talking to me and it's an active forum, constantly active, and i almost feel like my question is just getting ignored. Not even giving me an answer of IDK. I got somewhat of an answer from someone, but i wasn't sure, and no one ever got back to me, so I'm posting it here. I have put off playing until I find out for sure and no one will help me!

Alright so I'm going for the cheevos that require neither killing or being detected. So that checks off Shadow and Clean Hands, but the description for Ghost is as follows "You completed all missions after the prologue, alerting or killing no one but key targets." So do I HAVE to kill and/or alert the key targets to get the achievement, or will completing Shadow and Clean Hands unlock Ghost? Can I just not kill or alert the key targets and still get it? I don't want to do a SECOND stealthy playthrough of not killing or alerting anyone and just kill the key targets, that almost seems like a wasted second playthrough. I want my second playthrough to really get into the cool powers and gadgets of the game and killing people.

What it's trying to say is that you will not be penalized (not get the acheive) if you kill only your targets as the nonleathal options are less obvious.