Since there are no scheduled quests in this game, thankfully, I don't pay attention to the time. In the old days, settlements were about 10 to 15 miles apart as that is what a person could be expected to travel on foot laden down with goods. Horses came along and that went to 30 miles in spacing, and with trains, it went to 60 miles (for water refills).
So, how long would it take you to walk 10 to 15 miles, the distance I would expect there to be between major cities in Skyrim? Or, how long would it take you to run? Figure a 6 minute mile for running, and a 15 to 20 minute mile for walking.