Right before the first mission, after obtaining my powers I noticed a note in Piero's lab, by the door with the portal shaped paint. It goes on to explain how he believes he can create a doorway that will allow you to cover large distances, but this technology is years away. He also says if he survives the plague it is sure to succeed.

What do you think this is? I'm assuming its going to be how we access future DLC, in distant lands

Considering Piero actually survives (I think), I guess it could be a future DLC. I haven't put much thought into it though.

This is my 2nd playthrough and I'm just noticing it now. I just find it interesting since it doesn't mention it at all later in the game (I think). Which is why I assume its for DLC access

It's a reference to Portal I believe.

That's what I thought, too But then again, nowadays anytime someone mentions a portal I always think of the game...

Before discovering that the few powers shown on the powers menu were really all there were, I had hoped there would be a way of getting through those doorways... Or maybe even those "white" walls that are around there. But no.
I haven't found that note yet myself, but yeah does sound like a Portal reference.

Pfftt, had me going there for a moment, you taffer!

Perhaps Perio is the true inventor or the portal gun, but his first attempt at creating it hurled him into the future! He then landed in one of Apertures testing champers, made some quick adjustments to his prototype portal gun then used it to beat the testing course! Astonished by this Cave Johnson offered Perio food and shelter in exchange for his mind!

You hagfish!

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Err yeah, that's what this thread is about...

people are talking about the clues and text that is given in game to the door to knowhere, they never mentioned the brick wall with the logo...at least i dont think so

^{ah my bad, i feel stupid}

No prob everyone makes mistakes.