Ok, I've been banging my head on the wall for hours because of this and haven't found a solution yet. I have this perk applied to several different creatures, basically it doubles the damage dealt to the creature depending on the weapon the attacker is using. Draugr receive twice the damage from axes, automatons receive twice the damage from maces and so on.

Does anyone have the slightest idea why the SAME perk works as intended on Draugr and does NOT work with automatons? The perk is applied but it has absolutely no effect with no apparent reason.

Sounds strange. What are the conditions you put on the Perk?