With Zenimax giving it a shot, there's no telling what we'll see.
What do you want to see, and what do you expect? Points of interest would be visuals, sun mechanics, vampire buffs and powers, and relations with townsfolk.
Personally, I really enjoyed vanilla Skyrim. Dawnguard's glowing red eyes and bloody septum seemed distracting, and it didn't make much sense that it would make people fear you even less, especially given the increased fear of vampires lately. Thankfully the sun didn't mean automatic death as in Morrowind. Lacking damage altogether seemed strange, but the debuff was certainly a powerful effect. It seemed alright. But given that TESO is an MMO and players might always be stuck playing at a certain time of day, it could make vampirism pretty unfairly inconsistent among players.
I dunno. What do you all think?