Only just recently tried to start a new character and had this happening. Turning on TGM does not prevent it. Right after your character leans down to get his head chopped off (and the game gives you control of your character) my PC instantly dies and the game reloads from the last Autosave. In this case the first Autosave of the game.

Here is my mod list. I've begun turning recent mods on and off but so far nothing. Any ideas?

GameMode=Skyrim

Skyrim.esm
Dawnguard.esm
JSwords.esm
SkyMoMod.esm
moonpath.esm
SPIKE.esm
Update.esm
HighResTexturePack01.esp
HighResTexturePack02.esp
Lady of Death.esp
WATER.esp
breezehomelightfix.esp
Vampire Lord Serana Fixed.esp
Cloaks.esp
Cloaks - No Imperial.esp
Cloaks - Player Only.esp
Dread Knight Weapon Set.esp
JoOsSkyrimKnightlyArmory.esp
JoOsSkyrimKnightlyArmoryCheat.esp
Realistic Lighting - Dawnguard Patch.esp
moonpath_questdata.esp
The Dance of Death - Dawnguard Edition.esp
FNISspells.esp
dD - Enhanced Blood Main.esp
hothtrooper44_ArmorCompilation.esp
Unofficial Skyrim Patch.esp
StaticMeshImprovementMod.esp
Unofficial Dawnguard Patch.esp
SkyUI.esp
RLO - Dungeons for ELnFX.esp
RLO - Illuminated Spells for ELnFX.esp
RLO - Major City Interiors for ELnFX.esp
RLO - Minor Cities & Town Interiors for ELnFX.esp
Realistic Lighting Overhaul - 3.5 Dawnguard Weathers.esp
Realistic Lighting Overhaul - 3.5 Weathers.esp
Dovabear.esp
Immersive Weapons.esp
Vampirelordroyal.esp
VLCollisionFix.esp
Duke Patricks - Heavy Weapons Combat.esp
iHUD.esp
vampirelordwings.esp

Well, I found the culprit: It's Duke Patricks Archery and Heavy Weapons mod. Either I've got it installed incorrectly somehow or it's not jiving and killing me!

His mod looks amazing. Any help or tips will be appreciated. thanks.

It could be anything once you have that many mods, you probably messed up bad downloading all of those. EDIT nevermind lol.

I've found the new game sequence doesn't play nice with having lots of mods installed. Disable as many as you can and then enable them after leaving Helgen. It should help things

That's a good idea I'll try that. Thanks.