Alright , first up I've upgraded to win 10, i did have an issue with my screen going to the left loosing half the screen, reso issue, however now i have an issue when i window out i can't window back in, it won't allow me which forces me to force shut down the game and go from last saved game which is annoying, also i only recently had an issue after stealing a few objects in the game, my pitboy won't respond with my mouse, only by the keyboard keys thats it same as the menu.

It's generally not a good idea to alt-tab to desktop anyway. Why do you need to?