When i get to the part of the quest where i am to go stand in the glyph karliah doesn't go open the door she turns around and walks out of the nightingale hideout. Something that also happens is that the dialog between Brynjolf and Karliah start over as she walks out. Anyone got this as well?

I'm having the exact same problem. Brynjolf and Karliah leave the cave before opening the gate and letting me stand on the empty glyph. I dunno what to do about it.

For me only Karliah walked away, so I loaded a recent save and followed her. We went north to Riften, through Riften and continued north. We went through Shor's Stone, past Shor's watchtower and started heading west. Went past the Mzulft ruins, and lost her when I saw some mammoths and giants. I returned to Nightingale Hall to see Byrnjorf still standing there.