I WAS able to recreate it without the texture pack but it took alot longer and some nvidia inspector tweaks were on like ambient occlusion and 16x af and 8x msaa. Tried for 5 minutes loading new areas vanilla and couldnt get it to happen thought I wont rule out the possibility that it could because it wasn't that long.
It's really easy to create for me at winterhold college going from the dorms to outside about 5 or 6 times. My 60fps would eventually half after loading the area where it was 60 the last time it loaded. Alt-tab and its back to 60. Don't know if the driver (295.73) is at fault or the game. I did have a similar situation in Batman Arkham City but I just had to alt-tab once and it only happened one time so I'm completely confused.

