I am now over 20 hours in game, I have been in the strip. I however left for awhile to do a lot of side quest, then finished the boomer quest and went to turn it in, however anytime I enter the strip main gate, the game crash's on me. If you guys want details...

I finished the fly with me quest(the one where the ghouls fly away with rockets)
I have all the companions except for the scribe
I did use the lvl up exploit during that atomic wangler(sp) quest to lvl up two levels.
I did kill Gloria before I went to give that evidence to that NCR guy in the outpost
I didn't kill House, but did start doing the quest for yes man around the strip, haven't been to the Legions fort yet so the main quest is put on hold.

These are the only things that I could see causing issues. I have done a lot oft he side quest. I hope this will be fixed or something because this is game breaking for me, and I really don't feel like making a new character until after I beat the game with this throwaway character. Just bringing this to your attention developers.

I haven't completed quite as much as you have, but I reached The Strip last night and am encountering the same problem. I've searched around, but no one has been of any help, and lord knows when Bethesda will say anything about this issue.

I simply can't enter a Casino in the Strip, as the game freezes. Unfortunately, two quests require me to go into there, one being the main plotline. So I cannot progress in the game until this company comments on a fix.
:(

I just don't get it because I have been in the strip a lot, now all of a sudden it''s like my game said [censored] you, we will now crash the game and stop you from progressing in the story.

It's good however that I am not the only one running into this, maybe this will be fixed since this is a major bug.