BO team mentioned:

"On consoles, we are aware that a small group of 360 users are seeing a DLC warning which is preventing you from loading save games. We are absolutely looking into this bug now, along with other reports of save game corruption. It is our highest priority right now that we find out what is causing it. In the meantime, we recommend you save often, and revert to an older save if this occurs."

I just wanted to mention that "small group" may be an understatement. I suspect "many" of us fall under the category as "first time caller, long time listener". With that, I'm now compelled to contribute to the discussion.

I too am having this problem. Being a software engineer, I know how difficult certain bugs can be to track down. Here is some info that I would like to pass along to you:

1. The bug occurs the moment I complete the "Come Fly With Me" quest and I save the game. That game and all subsequent saves fail to load.
2. I get the bug regardless of whether I'm logged into XBox live or offline.
3. I have a second Xbox live account. When playing through that player, I am successful in getting past that quest.
4. I orignially had Fallout 3 with every DLC available. I deleted ALL that content before running New Vegas.
5. I beleive the Space Suit has nothing to do with the bug. I kept it in my inventory, took it and sold it, and never touched it. I all three scenarios, the bug appeared.

I hope this helps.

I would hate to break into Manny's terminal to continue the quest, so I patiently wait for a fix (and kill a few radscorpions in the meantime).

Thanks!

Completely wrong game.