I'm running New Vegas at at 1680x1050 Ultra on an 8800GT at full 60fps (vsync) outside and an average of 40 around NPCs. Everything is cranked to maximum with the following exceptions:
AA is 4x
Water reflections & refraction are turned off.
Smooth like butter! Not bad at all for a 3 year old machine. Intel Q6600 2.4ghz, 4GB of ram (320GB 7200rpm primary hdd and a 1.5TB 5900rpm secondary I use for archive storage and Fraps captures)
This is using the d3d9.dll fix - before that I would get 60fps outside and as low as 8 when more than a couple of NPCs were on-screen.
The d3d9.dll 'fix' forces an earlier, more primative video mode.
Therefore, your 'cranked to maximum' and 4xAA are phoney.
Instead, you should use all the latest drivers (including DirectX), disable AA and Vsync within the game and run medium or low settings if required.
@Magnificate
Do you have nVidia or ATI?
Important to launch the game with high-performance settings in the nVidia Control Panel or ATI CCC.
Do not set to force vsync, AA or AF. Always set 'application controlled'.
Set for max performance, all variables.
Disable Win7 Aero effect before launching.
Play full-screen using very modest resolution and game video preset, no AA, maybe 4xAF.
Once you establish smooth, fluid performance at meek settings, you can begin to experiment with higher settings.
On my rig I get 60fps minimum - and avg. & max. are much higher.
I use 1680x1050, no AA 4xAF, no vsync, medium settings.
Very smooth and fluid, and looks fantastic too.
Regards