I made a very simple higher damage mod (changes the fdamageskillmult from 0.5 to 1.0), and it's on Newvegasnexus. When I first uploaded it, I didn't realize I had my caravan pack ticked as a master file, though, so at first players had issues with getting this very simple mod to work. I fixed that this morning and now I am confident in advertising my little mod (my first mod!) to the general gaming community of this forum.

I present, (with far more ceremony than necessary for the most simple of all mods):
http://www.newvegasnexus.com/downloads/file.php?id=35004

This probably throws DT right out the window. Myself, I went the route of globally reducing everyone's health. Same end effect, different path

Of course mine ends up making fighting armored opponents without proper equipment to do so quite... difficult.

I'm not sure how exactly this affects fighting armored opponents. I suppose you simply do more damage, and therefore penetrate armor more easily with any weapon. I havent fought anyone in power armor yet, but I would venture to guess that this mod would make improper equipment vs armored opponents perhaps a little more forgiving. Regardless, while you chip away at the health of a guy in heavy armor with 50% more damage than before, he's shooting right back at you, and just as hard, so it might all be a wash in balance either way.