Hey, I'm stuck in vault 22 after you decide to help Keely. I found where the gas is leeking out and where I need to blow up, but can't figure out how to blow it up and I'm no longer able to leave the vault. Help? I don't even know what I'm supposed to be looking for because that dumb Ghoul didn't tell me [censored] other then "Blow it up and survive"

This is how I did it, but I don't know if you'll be able to. If you follow your map down to the bottom floor (Level 5 I believe) you will find some vents that are marked on your map, and should be able to see gas fumes in the air. If you back up and are facing the air ducts there is a room to your left, the same room where you previously downloaded the plans from the computer. I stood in that room by the door, and tossed a grenade near the air duct then immediately closed the door to the room. Everything blew up, but because the door was closed the fire did not get in. Obviously this only works if you have something along the lines of dynamite, or a grenade. Hope this helps.

See that's what I was afraid of, I don't have any of that on me, and it's not letting me leave the vault.

Figured it out. You can stand in that room and shoot any gun like the plasma rifle and blow it up from in there. Thanks for your help