Unfortunatelly, I've encountered a problem after many (50+) hours of more or less smooth gameplay.
All the saves containing my newest character (quicksave, autosave and all normal saves, including one just after being woken up by the Doc) won't load but cause a CTD after 2-3 seconds of the loading screen. All those saves worked well earlier, I mean they did load properly. They just stopped loading after a random CTD in the areas of Goodsprings (thankfully it's only a starting charachter, so I'm not as frustrated as I could've been).
However, after creating a completely new character and quicksaving the game (after being woken up by the Doc) that save loads properly.
Reinstalling with no mods or restoring game settings to default (I had them tweaked a bit for better looks) did nothing.
Any idea what might have caused this? It seems really strange, having a whole character broken, not just one or two of the last saves (like with the Come Fly With Me problems I've been reading about).
It's not a huge problem to start a new character, but I'm afraid this might happen again.
Any ideas?