Spoiler
The Chosen One from Fallout 2. Not only is "That Gun" present in the Mojave, (A gun used by both The Vault Dweller and The Chosen One) but just South of Novac, you can find a broken down "Highwayman". Not only this, but No-Bark makes mention of learning a spell that makes people's true forms show, which he learned from a Caverat. HELL! He even mention Wanamingos, from Fallout 2 when asked about The Guy in the Checkered Suit. Is it possible that, after starting his own town, The Chosen One heard of New Vegas, had some bad luck, and ended up as this crazy old coot? 40 years later (2241 - 2281) and this is what the Chosen One has become? It seems plausible to me.
