Everywhere else in the game is fine, no random crashes. In this casino however I experience hard lockups frequently. What I mean is the game freezes with the audio looping, no exception is generated by Windows however so I have to end the game via Ctrl-Alt-Delete.

Can people please post ways they've gotten past such issues?

Apparently there is a MOD to fix the worst location in the Ultra Luxe Casino (Steam Room) but I have yet to try it. Anyways Obsidian needs to fix this bug properly as the mod seems to resolve it from lowering the water level preventing characters from swimming... thus changing the bathroom experience for players.

http://www.newvegasnexus.com/downloads/file.php?id=37351

For the curious, that is the MOD I used and it resolved the crashes for that area perfectly.