There are a lot of glitches in the game, but they've all been minor things, relatively. A quest being unable to complete, stomach cam, a few freezes, but the one that I really have a major complaint about, and I hope it's not just me, is that ever since Honest Hearts has been released, at least 40% of the time I go into gunfights, my bullets seem to pass right through my enemies. Every once in a while I think it's just that I miss, but after a few more instances of it, and even going into Vats, this has occurred a lot.

I'm not sure if any one else was aware of this, I assume that there are, but this is the biggest game breaking bug I've come across, so I want to be sure I do what I can to get it fixed.
Thoughts? Or am I just crazy?

I've experienced that too. I'm waiting until the patch to see if it happens less. If not, maybe we're just missing alot? Those giant cazadores are pretty quick...

I still think that the worst glitch ever is the one that every single lever-action weapon has. And the hunting shotguns: When you're reloading you freeze then when you go into third person you're slowly walking forward... :brokencomputer:

The one where it freezes on the loading screen never quite sure since sometimes it can take 2 or 3 minutes to load so those svck, or when you get stuck when finishing a vats attack and your unable to move but everything else goes back to normal usually only lasts 20-30 seconds but its long enough to get killed fourtunatley that kinda rare.

Still, freezing up is just freezing up. Don't get me wrong, I've had infuriating situations like that of traveling from one end of the mojave to the next only to have to re do it all cause I had the gall to switch ammo types. But, it's still just a freeze. It doesn't directly affect the function of the game.

Plus, I'm a looter. So when my precious ammo goes wasted, I feel the pain deep in my soul. It doesn't matter that I have 9000 rounds of the .45 Auto, so I have bullets to spare for at least 5 comrades (Thank god for not hardcoe mode), BUT, when I unload an entire clip trying to kill a Feral Ghoul, and it all just passes through him, or doesn't even hit, I get more upset than when the game simply freezes.

I certainly hope the patch fixes this. This bug didn't exist for me till Honest Hearts. Maybe it's a sign that I should resort to less violence....

*Goes to decapitate and cannibalize corpses.*

I was going to say I've never experienced this before, but after testing this on Raul, I can say that yes, I get it too. Hopefully it gets patched along with the other stuff
Edit: To test it for yourself, save, then start throwing stuff like tomahawks, throwing knives, etc. at your companion.

My worst glitch is when I am rock climbing to sniper deathclaws, then I seemlessly stop. Turns out I am infinately falling in the same spot and cannot fast travel or any of that stuff. You can't even dislodge yourself.

You can if you're on a PC, via use of the 'tcl' console command. Those on console systems are hosed, though.

I rarely have glitches, but the worst one is easily the 'Highlander' glitch, where your target turns immortal and sits there beating on you with a clearly empty HP bar while you empty multiple clips into it in a vain attempt to put it down. Bonus points if the attack that 'killed' it was a one-shot. Fortunately, the 'kill' command fixes the problem; I tend to couple it with the 'disable' command in order to keep it from respawning and possibly doing that again, although that's probably overkill.