My game crashed at startup and stated an opengl related error. I disabled multi-GPU and the game has ran great. I only have one graphics card and about 6 out of 10 games I have to disable multigpu or I have problems. I hope this helps some people.

full specs
Motherboard: Asus P5N-D
Chipset: nvidia nforce 750i SLI SPP
Processor: Intel Core 2 Quad Q9650 @ 3000 Mhz
RAM: 4096 MB DDR2
VideoCard: Nvidia Geforce GTX 295
SoundCard: Creative Sound Blaster X-Fi XtremeGamer
drivers 280.26