Probably wise, I mean I have been a TES player since Morrowind and even went back and played Daggerfall so I have some idea, but as you put it enough things do tend to change from one game to the next that it requires a bit of re-education.
ya. one major change that has bothered many people is mages seem to be a bit more challenging this go around. some have a great deal of trouble figuring them out (just check for threads here and in general), while others seem to have no trouble. in oblivion, it was pretty easy to play a mage and once you hit a certain point you were basically untouchable. guess that's not the case here and it takes a bit more work. i have a mage that's 23 right now and i've not had any major issues yet but from what i hear it's at higher levels where the difficulty comes in.