I've mapped the WASD movement keys one key to the right: ESDF. I do this so that my left hand is in the default typing position, which gives me easier access to the other keys and makes it easier to remember what keys I've mapped since that's how I type anyway.

Here's the bug. I've mapped V to Quick Magic, and when I hit it and select a spell and then hit F for Favorite (as it says in the lower-left corner of the screen), the spell overlay menu closes. In other words, because F for me is move right, the game is interpreting the key as though I want to close the overlay rather than use Favorite. (Even though the interface help in the lower-left corner says F for Favorite.)

Likewise, if I hit G to open my Quick Inventory and select and item, hitting F does nothing.

It's possible I'm simply doing something stupid, so please let me know if that's the case. Otherwise, I'm hoping there's a workaround as I play all first person games with the default left hand typing position. I recommend trying it if you typically map a lot of keys -- it's easier to remember them and reach them. Thank you!

P.S. I don't use any interface mods, and I don't have Dragon Script or SKSE installed.

This is 'normal', Bethesda made a very good game, with the worst and buggiest user interface I have ever played, and at the moment, they refuse to fix it in a patch.
So, bottom line, do not remap keys, or find out by trial and error what key is swapped to what function, and don't look at the displayed key mapping hints of the game.

Ouch, discouraging. I've seen some patches on Nexus to fix Xbox controller mapping bugs, so maybe somebody will fix the key remapping. Is there any chance that using SkyUI would fix these remapping bugs?

Fix here: http://skyrim.nexusmods.com/downloads/file.php?id=368

The key fix mod works for the most part, but there is a bug. As I mentioned, I remap my WASD movement keys one key to the right so that my hand is in the default typing position. In using themod, I found when I came to a book, W opened it as expected, but then overlay said E to take the book, and that didn't work. I had to hit W again to put the book in my inventory.

Pm the author, it's probably still a WIP

your move right is F, fav also F? can't remap fav?

Yes kelmen, my move right is F, and the mod does fix the fav mapping. It's just the book issue I described above that's not working.