The problem is that I should be able to run supersampling (my computer is more than capable of processing it), which you can't do in-game, but it's not working with Skyrim (it artifacts all over the place). Adaptive MSAA works, but you can't use the "enhance application settings".
I completely get it, since I have the same thing. That's why I said in-game FSAA is the best you can get now. Maybe AMD will get their collective heads out of their bungholes and fix this someday.
In the meantime, you might not get 100% jaggy free image, but you do get better FPS than with SuperSampling. Some people also have said to combine FSAA (like 2XAA) and FXAA and they are happy with the results.
@http://www.gamesas.com/user/617321-tgl1992/
I think http://www.gamesas.com/user/668485-earwicker7/ was referring to the specific Skyrim NVIDIA Tweak guide.