I've got Skyrim running on my system with a 7.1 surround system, and when I play I only get 5.1 surround, with my side speakers producing no sound at all. My sound card is an Asus Xonar D2X, and I'm using all anolog outputs for the sound. Even with GX mode on, the side speakers don't make any sound. I've checked on Mass Effect 3 and the speakers are definitely hooked up and useable by games.
Any ideas what might be causing this stuff?
I can provide more information if needed.