So here's the deal, for the last couple of days, ever ytime I am on the road between Honningbrew Meadery and Valtheim towers, about a little less than half-way to the tower, my game freezes...completely. The only way out is to ctrl-alt-del and bring up the task manager (which shows Skyrim - Not responding). This happens on any character, existing or new. With mods and without, with ENB and without etc etc. I have tried everything I can think of, but no luck. I have not made any changes lately that would cause this. As a side note, it happens occasionally outside of Riverwood (the guardian stone side), and occasionally in other random spots, like outside Windhelm once in awhile, but not EVERY time like the other spot.

I have a pretty nice system too and run the game between 45-50 FPS most times, with HD textures and on ultra settings. Turning those down does not help either. Here's what I use:

Windows 7 64 bit
i5 2500k @3.7 GHz
16 MB of Corsair Vengeance RAM
AMD 6950 HIS IceQ Turbo w/2 GB of VRAM
Gigabyte Z68-UD3H-B3 MB
850W Coolermaster PS
Intel 120 GB SSD

Still using version 1.5 of Skyrim. Thinking about trying the 1.6 Beta to see if that does anything.

If anyone has any ideas, I'm all ears. It's getting very frustrating. Please help!

PS, have tried things like Gamebooster too, but that does nothing.

Let me guess, your not uninstalling the mods, but just unchecking them in the Launcher? Some mods have to be uninstalled, especially any mod that changes graphics and uses an ESP. Texture replacers usually just give large yellow exclamation points, but the game still runs when those are messed up.

Stock, the only reason these games crash in a certain area are script related issues. Waiting somewhere for 73 game hours usually clears that up. If that does not fix it, then it is your mods that are causing this.

You may have to bite the bullet and uninstall and reinstall the game. Then, use Wrye Bash to install and adjust the load order on your mods. You might try fixing the load order issue before the reinstall using something like BOSS.