You don't necessarily need any perks to cast one, it's something anyone could use. 2-4 perks can improve them quite a bit - augmented fire/frost/shock+dual casting.
So I figured I'd try it on my high level character. I'd been turned off destruction from the forum's reactions to it, but runes had sounded interesting to me and I thought "why not?"
Turns out, it's a complete waste of time. Even using a poison of weakness to an element or magic, a single arrow does enough damage that wasting a bind + time on using runes just isn't worth it. I could do it just for "RP" reasons but it seems hollow.
Personally I feel like the range between full specialization and none is too wide in many cases. An archer with perks and 100 skill does more than 200% damage of a starting archer, add high end gear and enchants and it's even more. It would become pointless for that character to use a melee weapon to defend themself vs. a scaled enemy if one happens to close in, because a melee weapon does equally pathetic damage at low skill/perks as that rune does. It's almost completely pointless for them to use a destruction spell as well - even one with essentially no cost in time or resources.
Obviously, spending perks in a skill's tree and increasing that skill should improve it, but I think in many cases in Skyrim skills can be improved so much they end up simplifying gameplay. A low level archer would get a lot out of casting that rune, and would often be better off using a melee weapon in melee range. A high level archer is better off just shooting things exclusively, even at point blank range.

