So I've been playing with enchantments, and I got to wondering. If at level, let's say, 25, you had the option of creating an enchanted item that fortifies destruction (or another magick skill) 12%, or increastes total magicka by 50, which would you choose? I've got two items right now that reduce my magicka cost for destruction by 27 (15+12). I can create another +12% reduction item, or use a hood (adept) that increases total magicka by 50...which would be the best option?
The best option is to create two items that reduce costs by +12%

Not kidding, you should be able to put cost reduction enchants on 4 armor parts total and you only got 2/3 it seems

Anyway, answer to your question is hard because we kinda lack information. First, how much base magicka you got already? If you only have 100, then the +50 effect is probably the best for now. I'd say, go for the enchant that allows you the highest number of spell casts in a single magicka bar with the advantage for cost reduction if it goes somewhat even because it also saves you magicka pots in the long run : casting two nukes at -50% for a total of 200 magicka is better than cast two nukes at -0% for a total of 400 magicka because it costs you fewer pots to restore it

It makes you more vulnerable to shock damage drain though.