Horkers.
They're really ugly, fat, slow, easy to kill, and although territorial, usually neutral.
I always feel bad when I get too close to a Horker and initiate a battle, in which my companion insta-kills the Horker with a brutal sideways, head-severence.
Anyone else feel some sort of sympathy (possibly empathy if you're a computer hardened animal) when a battle accidentally engages with any neutral beings, on the Skyrim landscape? (Horses, Cows, Dogs, Chickens, Foxes, Deer, Elk, etc.)
Maybe when I play a more evil-ish char it will be different, but with my current good-aligned one, I don't even kill bears, or sabre cats, if I can avoid it. I use the Kyne's Peace, and that's it. Only animal I kill are wolves, as long as I need to walk in their area. Else I just leave them be.
About horkers, never got attacked by one because I always keep my distance. Once I heard the combat music and I just walked away. It's their area (or home) and I'm the intruder.
Just a few days ago I killed a horse by mistake, and didn't feel good. There was a Spigran far away, so I took my bow and aimed at it, but it was just behind a horse, that was instakilled.
About sympathy? Well, giants are ones I respect. They are on their own bussiness, and only become agressive if you go too near. A few days ago I went to complete a quest give by a Jarl, to kill certain giant. I went there and I found the big guy on the fireplace, scratching his back, waiting for a cow to cook. I walked around with no reaction from him. I got nearer and he went into a defensive position, moving his club and telling me to back away, and all this without even attacking me. After a minute of threatening me with his club, keeping clear that I was invading his home, I decided to walk away and let him be. "Problematic giant that needs to be killed?". Nah.. I'm sure the 2 dead guys around the fireplace just went there to break his balls.
Anyway, things will be different with other chars I will play when I'm done with this one.