My Nord warrior has managed to get 4 Whiterun citizens killed so far: Adrianne Avenicci, Idolaf Battle-Born, Mikael, and Uthgerd the No-Longer-Unbroken. I'm not sure, but Adrianne and Idolaf I might have killed during my first werewolf rampage. Oops. The other two died during a journey back from Riften, where they'd joined the wedding party when I married Ysolda. Mikael was killed by a bear, and Uthgerd was done in by a frost spider. I was rather disappointed in Uthgerd, but she was probably low level. They probably would have been ok if I'd FT'ed back to Whiterun, but I wanted to see what would happen if I went along.
The one I feel the worst about is Adrianne. She made me her heir, and Ulfberth is sort of lost without her, since apparently he's not a smith himself. I'm going to make up for that by being his smith. I'll buy the raw materials from him and sell the finished products to other merchants. I'll be sure to put flowers around all their coffins/urns in the House of the Dead.
So, what named NPCs have you managed to get killed accidentally?