If you are shooting from an extreme distance, arrows can occasionally pass right through targets. I've wasted dozens of arrows on wolves trying to perfect my shot only to find that out later.
That is because, despite archery actually being the best way of damage-dealing in Skyrim..... the game was designed with running up and hitting things with axes / swords in mind.
Because Bethesda got tired of putting effort into their games, and decided what we really needed was some really generic "Hit Dragons With Swords" action, like every other fantasy game in the freakin Universe. The ability to take things out from range was just an afterthought.... and past a certain point, it is assumed that you won't be trying to attack something because it is too far away (i.e. because you're not close enough to hit the dragon with the sword).