Background.

So what is it that defines the Dragonborn? The usage and power of his voice, his thu'um.

Unfortunately in vanilla Skyrim, due to it's inherent easy-mode game balance features (smithing, alchemy, enchanting, over-abundance of gold/equipment, kill Dragon with bow and arrow at level 6) coupled with poor enemy AI, enemy lack of perks and low-damage that using Shouts was something I never used or needed. Additionally, the effectiveness of shouts could not be altered with perks, thus they remained static with a lot of them becoming ineffective at higher levels or requiring too long a cool down to use often.

In response, SkyRe (Skyrim Redone) reworked shouts making them more viable. The magnitude, duration and cool down of shouts can now be increased or reduced within the modified Speechcraft skill tree. Heralding the entrance of the....

...Dragonborn Build.

Race - Male Orc (Slim Physique)
Racials - Berserker Rage; Orc Smithing Lore (25% Smithing tempering).

I choose this race because of the Orc Smithing Lore racial. In SkyRe, to gain 25% tempering to weapons and armour, it would cost me 4 perks (2 in weapon tempering and 2 in armour tempering), this racial saves you from investing 4 levels into this tree that can be uses elsewhere.

Standing Stone - Warrior Stone (+20% skill increase in Warrior skills) or Lady Stone (+50% health and stamina regen, -50% magic regeneration).

The Lady Stone is a very good option. This build does not require magic usage so the magic regeneration is not that important and if you choose to use Restoration then you will still have enough magic if needed, just have to wait longer between battle if you get hit too often and/or drink magic potions.

Primary Skills - Light Weaponry, Speechcraft & Block.

This is a one-handed weapon/shield build Allows for fast attacks, bashing, blocking of physical attacks and elemental resistance. Most points will be put into Speechcraft and Light Weaponry for damage output and versatility with shouts.

Putting points in Speechcraft has three main benefits;

1. Effects magnitude, duration and cool-down of shouts.
2. Versatile game-play - You have TWENTY shouts to use at your disposal; Ice, Fire, Slow Time, Elemental Fury, Become Ethereal and much more!!
3. No need to keep having to run around with spells anymore, I hate having a spell constantly in my left-hand. Unfortunately they didn't do it like Oblivion whereby your spell-hand would unsheathe once the spell was used. It also removes the need to keep swapping out from shield, spell, shield, spell. Shouts remove all this 'hassle'.
4. Makes collecting dragon shouts and killing dragons a mini-game and exciting to do!

Secondary Skills - Light Armour & Smithing.

You will be mostly a melee-based character and therefore improving equipment will be important for increasing damage output and damage reduction. Fortunately, some of this perk investment is mitigated by your racial ability; Orc Smithing Lore.

You can choose either Light or Heavy Armour, however SkyRe slows down the character further with Heavy Armour and Steed Stone no longer provides weight reduction so you will feel slow all the time. I prefer speed and some of the Light Armour perks. I plan on using my shield to block attacks so if you play well you won't keep getting killed.

If you have any thoughts/impressions on this build and we'll discuss ...

My Challenge Mod List

Have you tried playing the game with this to get a feel for what the experience is like and so you can offer perk recommendations? I honestly dislike playing "theoretical" builds that have no playtesting so I'd like to get a feel for how this plays through the game from low to high levels.

I've played around 10 hours with a spellblade and 20 hours with a Thief type and so I have a feeling for what would and would not work in SkyRe.. but like you said this is a theoretical build.

In a few days to a week I will update this thread with perk recommendations and list what challenges are likely to be faced.

With SkyRe coupled with other challenge enhancements the world is too dangerous you wouldn't believe it. I really had to think long and hard about this build because all typical standard warrior/thief builds have a difficult time as they are not flexible enough. I wanted a build without magic because you really need to block damage and I hate the constant glowing hand on my screen and the constant switching of shield/spell/shield/spell... ad nauseam. The spellblade wasn't fast enough in Light Armour to dodge all attacks so died very fast if hit, no shield to block damage, constant spell swapping, health/stamina/magic spread too thin and too many trees needed to be invested in.

Thief type was good but you can rarely kill anything in one-hit even in a Sneak attack and even if you did then all it's buddies would run up to you and destroy you. You cannot kite fully as well as SkyRe changed backward moving speed. Even with high Alchemy poison they didn't kill fast enough and didn't have enough for the 30 amounts of enemies I was always facing every 1-2 dungeons let alone all that is in the wilderness.

With the Dragonborn Build I predict it will be not too challenging at lower levels, but at higher levels (40+) once you have most the skills you want in the five skills I listed then you can begin to put points in enchantment. I will evolve the build when I get there.

I have updated my OP to include my challenge mod list.