So after a period of 50 years, they'd have an idea of how ten vaults worked, but they'd be trapped in theirs, unable to help. Would they go completely mad? Would they form some kind of heroism complex? It would be fun to get a psychology student on board for this as well, to write detailed anolysis of certain vault residents and their degradation over a period of time. It would require quite a bit of story-telling as well.
The end result would be basically a nice way to bring previous Fallout games and Van Buren into New Vegas. Just a thought, anyway. I figured I'd toss that out there.
