It means nothing. The patch affects the .exe only, making it unable to launch without validation through Steam. This broke the ability to temper with the .exe itself by, say, flagging it for large address awareness, as Steam will refuse to recognize a modified .exe, but modding depends on .esm and .esp files and assets (meshes, textures, sounds) added to the Data folder, not the .exe itself (except for script extenders, but there is a workaround for these as well). Even the main game is an already existing .esm in your data folder. The .exe just exists to load these. The patch has no reason to prevent .ini tweaks either. Hope this helped you understand.