As a female Dragonborn, I married Wilhem (the Inn keeper in Iverstead) and had us move into my home in Whiterun.
All of his dialog options are still there (specially the ones from when he used to be an Inn Keeper) which I guess it would be normal since he is an Inn Keeper, still have food to sell and rooms to rent.
So just for giggles, while in my own home (Breezehome) I decided to talk to my spouse (Wilhem) and decided to "rent a room for 10 gold". He takes the money and proceeds to "Show me to my room" which he promptly leaves Breezehome to go outside (I follow) and once outside he says:
"Is there anything I can do for you, love"
And then goes back inside Breezehome.
I thought that was incredibly funny in a "You should know better than to rent a room in your own home and how dare you suggest such a thing, you are sleeping outside!"
What sort of thing have you encountered in Skyrim that has made you laugh out loud? (can't be a glitch/bug)