That Autosave only works if you bring up the menu. Not even sure if you bring the menu up and it saves, or you have to bring the menu up every 15 minutes or whatever time you set it to.
It is really best to not have the Autosaves on, or only on one of the three other choices. You can Autosave yourself into a situation you don't want to be in, and they can corrupt over time. Better to use a series of manual save slots, like 10 of them. Use one slot for 30 minutes to an hour, then move to the next slot. Cycle back after the 10th slot. This way you can go back to replay a quest if it glitches or you want to approach it differently