I don't know much on how Skyrim threads scripts but I figure my reply is better than no replies

My thoughts on performance impact on scripting in Skyrim is that compared to all the graphical processing, the processing caused by scripts is surely irrelevant?
Skyrim doesn't have that many scripts in it to begin with, and you adding a few more wouldn't impact things I reckon.
What I'm trying to say is that the whole Papyrus scripting part of Skyrim isn't that complex and probably won't slow down the game much. It's much more likely that the game will slow down due to something graphics related (a weapon with 50000 polygons for instance).