I ran memtest, 3D Mark, played hours of spec ops: the line, starcraft II, and borderlands 2 on their highest setting without incident. I will probably reseat my video card after this, and I've ordered a tool to test my power supply from Newegg, but after that I'm out of ideas. The only other thing I can think of something to do with an update to the game.. but as far as I can tell there hasn't been one recently.
Any help would be GREATLY appreciated. It took me 2 weeks, working hours a day to finally get my mods running correctly originally. I REALLY want to play this game with mods on PC. But, I don't know what else to try at this point.
Here are my computer specs, in case they are helpful:
Intel Core 2 Duo Extreme X6800, 2.9 GHz
4GB Ram
NVIDIA GeForce GTX 550 Ti, 1 GB RAM